Macromolecular Interactions Facility

Description and application fields

The Macromolecular Interactions Facility (MacIn Facility) is a key research service of the University of Padua, housed in the Pharmaceutical and Pharmacological Sciences Department (DSF).

The research facility allows the study of biophysical properties and the macromolecular interactions of peptides, proteins, oligomers (DNA and RNA) and other macromolecular systems, that are currently being investigated as drug delivery vehicles (micelles, vesicles, liposomes, polymersomes, nanoparticles and so on). It provides a wide range of instruments and resources for biophysical characterization (size, shape, and surface charge analyses), for complex formation, for substrate affinity and for thermal stability of many different macromolecular systems.
Instrumental core includes: a spectrofluorometer; a circular dichroism spectropolarimeter; a surface plasmon resonance (SPR)-based biosensors; a microfluidic device to produce narrow-disperse lipid formulations; two dynamic light scattering instruments; differential scanning and isothermal titration calorimetry.      SCIENTIFIC EQUIPMENT – 

A staff of senior technical experts will provide training courses for students and researchers, and it will support academic collaborations and biotech commercial services.

 

Location: Pharmaceutical and Pharmacological Sciences Dept, Via Marzolo, 5 – 35131 Padova – Italy

 

Training courses

Specific training courses for researchers will be held by the staff, to make them independent in sample preparations and data acquisition processes.

 

How to book

All the researchers can book using the online system (http://147.162.61.199/) and log in with accredited credentials that will be generated after the training course (Certificate of attendance).

 

Facility staff and contacts:                       Sara Bersani, Ph.D. (manager)   sara.bersani@unipd.it

                                                             Phone number: (+39) 049 827 5360 (Mon – Fri: 9:00 a.m. – 5:00 p.m.)

Scientific board and research supervisors:    Prof. Gianfranco Pasut         gianfranco.pasut@unipd.it