CHNS elemental analysis, also known as “organic elemental analysis” or “elemental microanalysis”, determines the quantities of carbon (C), hydrogen (H), nitrogen (N), sulfur (S) present in a sample. It is a reliable and cost-effective technique for assessing the purity and chemical composition of compounds, which can be applied to a wide range of different sample types and solid, volatile and viscous liquids. It’s important for determination of the composition, structure and purity of organic chemicals present in pharmaceutical products, both in the research and development phase and in the production phase.

The vario MicroCube offers nitrogen, carbon, hydrogen and sulfur, determination by high-temperature combustion according to Dumas via a thermal conductivity detector (TCD). This TCD has been tuned for highest sensitivity, resulting in an analyzer that can quantify trace carbon and nitrogen with a detection limit of 10 µg/g or 10 ppm. Reliable results due to blank-free sample introduction, via “ball valve ®” and jet-injection of oxygen to the point of combustion which ensures complete conversion of the sample to measuring gas; a prerequisite for highly precise and matrix-independent elemental analysis.
Separation of gaseous components via our TPD® column. This column releases individual gases at different temperatures. The release of a gas is only initiated when the prior gas peak has reached baseline. This results in perfect peak separation without overlap, and automatic optimization of the analysis time.



Ultra Analytical Balance Sartorius Cubis MSA 6.6S-000-DM